Endocarditis caused by Actinobacillus actinomycetemcomitans
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چکیده
منابع مشابه
Endocarditis caused by Actinobacillus actinomycetemcomitans.
Actinobacillus actinomycetemcomitans is a gram-negative coccobacillus which is a very rare cause of bacterial endocarditis. Preexisting cardiac lesions are a main contributing factor, and antibiotic prophylaxis has long been felt necessary before dental or other manipulation to prevent endocarditis. Penicillin in combination with an aminoglycoside has been the most often used treatment regimen....
متن کاملSubacute bacterial endocarditis due to Actinobacillus actinomycetemcomitans.
A case of infective endocarditis in a 59-year-old female caused by Actinobacillus actinomycetemcomitans is reported. The organism was recovered from 9 blood cultures. Despite treatment with penicillin and gentamicin the illness led to destruction of the aortic valve.
متن کاملFailure of vancomycin prophylaxis and treatment for Actinobacillus actinomycetemcomitans endocarditis.
Reported is a case of Actinobacillus actinomycetemcomitans endocarditis which developed after dental prophylaxis with vancomycin and erythromycin. In vitro results indicated that this isolate and 20 additional isolates were resistant to vancomycin and that potentially useful bactericidal antibiotics for the prophylaxis and treatment of A. actinomycetemcomitans infections included gentamicin, su...
متن کاملSecretion of RTX leukotoxin by Actinobacillus actinomycetemcomitans.
Actinobacillus actinomycetemcomitans, the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages. Leukotoxin is a member of the highly conserved repeat toxin (RTX) family of bacterial toxins expressed by a variety of pathogenic bacteria. While the RTX toxins o...
متن کاملRelease of toxic microvesicles by Actinobacillus actinomycetemcomitans.
Oral isolates of Actinobacillus actinomycetemcomitans (strain Y4) release spherical microvesicles in large numbers during normal growth. The biological activities of these products were studied, and it was estimated that approximately 1/10 of their dry weight was made up of heat- and proteolysis-resistant endotoxin. The chicken embryo lethality and bone-resorbing activity of the microvesicles w...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1984
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.20.3.579-581.1984